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Web Interface: PICO (Patient, Intervention, Comparison, and Outcome).

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Abstract: 

PICO (Patient, Intervention, Comparison, and Outcome) is a fill-in-the-blank Web interface for searching MEDLINE/PubMed for information about conditions and diseases, interventions, comparisons of interventions (optional), and outcomes (also optional). A dropdown menu prompts for publication type from among clinical trials, meta-analyses, systematic reviews, practice guidelines, or, if none is specified, any of the above. PICO returns MEDLINE/PubMed articles responsive to the input.

PICO can also be used to structure literature searches. 

PICO is available through PubMed for Handhelds: http://pubmedhh.nlm.nih.gov

Fontelo P. Web Interface: PICO (Patient, Intervention, Comparison, and Outcome).