APPLICATIONS

APPLICATIONS

RxNav Overview

RxNav Views

Content

Overview

RxNav has a number of views (tabs) which display related information of the selected concept.

RxNav views (tabs) for displaying other related information

The Graph View is the default view and displays the selected concept with its related RxNorm concepts.

The RxCUI View contains the the status, metadata, and properties of the selected RxNorm concept.

The NDC View displays the National Drug Code information for the concept.

The RxTerms View displays the RxTerms vocabulary information related to the concept.

The Class View displays drug class hierarchies from several drug vocabularies.

The Interaction View displays the drug interactions with the selected concept.

Graph View (Graph Tab)

The Graph View is the default tab when RxNav is started. When the user enters RxNav, the options for the graph are displayed on the left, and the graph components to the right of the options. The default graph is the classic graph, which contains ten tables containing the RxNorm term types.

image of RxNorm graph

After a search is done, the RxNorm graph is populated with the concept found plus the related concepts.

The concept found from the search string is highlighted. By clicking on a concept in one of the tables, that concept string becomes the search term and all of its related components will then be displayed.

To populate the display, RxNav uses a set of default paths to traverse from the starting concept term type to find related concepts of the different term types. The path table shows the default paths used for each starting term type.

Graph Types
RxNav provides a classic graph view, a simple graph view and a table view, selectable under the Views label in the options:

RxNav graph views

The simple view provides two tables, one containing the ingredients and related products, the other for brand names and related branded products. The figure below contains the simple view for the ingredient ezetimibe.

RxNav simple view

The table view provides the same information as the classic view, but in a single table. The figure below contains the table view for the brand Celexa.

RxNav table view

Graph Filters
RxNav provides filters for the classic and simple graphs:

Graph filters

The selection of a filter implies that the graph should contain only those entries. For example, selecting Human means only those drugs containing the H or HV icon are selected for the graph. Selecting Human and Vet will result in only those drugs displaying the HV icon are selected. Similarly, selection of the prescribable filter (Rx icon) will eliminate non-prescribable concepts from the graph.

Group or Form Display
For the classic view, the user has the option of selecting either Group Term Types (default) or Form Term Types.

Group or Form TTYs

Links to other drug information

RxNav links for displaying other related information

Drug Label Link
This link provides the drug label information from DailyMed .

MedlinePlus Link
The MedlinePlus link allows users to view MedlinePlus drug information using the MedlinePlus Connect API. When the MedlinePlus link is selected, the MedlinePlus results web page is displayed.

Other Graph Symbols
The Legend provides other symbols which occur in the RxNorm graph.

RxNav Legend

MIN icon – identifies the concept as a multiple ingredient term type (MIN)
Pack icon – identifies the concept as a Pack term type (GPCK or BPCK)
Multi icon – identifies the concept as containing multiple ingredients

Download Button
The download button copies the information in the graph to a file with comma separated fields.
Download button

Default Paths

The default path table below shows the paths through the term types that are taken by RxNav to display the related concepts. (Note: these are also the paths used by the RxNorm API in the functions getAllRelatedInfo and getRelatedByType.)

The first and third columns indicate the starting term type associated with the selected identifier and the ending term type.
The second and fourth columns are the list of term types in order (the path) to get the related concepts of the ending term type from the starting term type.
Abbreviations
  BN - brand name     SBD - branded drug
  BPCK - branded pack     SBDC - branded drug component
  DF - dose form     SBDF - branded dose form
  DFG - dose form group     SBDG - branded dose form group
  GPCK - generic pack     SCD - clinical drug
  IN - ingredient     SCDC - clinical drug component
  MIN - multiple ingredients     SCDF - clinical dose form
  PIN - precise ingredient     SCDG - clinical dose form group


Default Paths
Start to End Path Start to End Path
BN => BPCK
BN => SBD => BPCK
 SBDF => MIN
SBDF => SBD => SCD => MIN
BN => DF
BN => SBD => SCD => DF
 SBDF => PIN
SBDF => SBD => SCDC => PIN
BN => DFG
BN => SBD => SBDG => DFG
 SBDF => SBD
SBDF => SBD
BN => GPCK
BN => SBD => SCD => GPCK
 SBDF => SBDC
SBDF => SBD => SBDC
BN => IN
BN => IN
 SBDF => SBDFP
SBDF => SBDFP
BN => MIN
BN => SBD => SCD => MIN
 SBDF => SBDG
SBDF => SBDG
BN => PIN[1]
BN => PIN
 SBDF => SCD
SBDF => SBD => SCD
BN => SBD
BN => SBD
 SBDF => SCDC
SBDF => SBD => SCD => SCDC
BN => SBDC
BN => SBDC
 SBDF => SCDF
SBDF => SCDF
BN => SBDF
BN => SBDF
 SBDF => SCDFP
SBDF => SCDF => SCDFP
BN => SBDFP
BN => SBDF => SBDFP
 SBDF => SCDG
SBDF => SBDG => SCDG
BN => SBDG
BN => SBDG
 SBDF => SCDGP
SBDF => SBDG => SCDGP
BN => SCD
BN => SBD => SCD
 SBDFP => BN
SBDFP => SBDF => BN
BN => SCDC
BN => SBDC => SCDC
 SBDFP => BPCK
SBDFP => SBD => BPCK
BN => SCDF
BN => SBDF => SCDF
 SBDFP => GPCK
SBDFP => SBD => SCD => GPCK
BN => SCDFP
BN => SBDF => SCDF => SCDFP
 SBDFP => IN
SBDFP => SBDF => BN => IN
BN => SCDG
BN => SBDG => SCDG
 SBDFP => MIN
SBDFP => SBD => SCD => MIN
BN => SCDGP
BN => SBDG => SCDGP
 SBDFP => PIN
SBDFP => SBD => SCDC => PIN
BPCK => BN
BPCK => SBD => SBDF => BN
 SBDFP => SBD
SBDFP => SBD
BPCK => DF
BPCK => DF
 SBDFP => SBDC
SBDFP => SBD => SBDC
BPCK => DFG
BPCK => GPCK => SCD => SCDG => DFG
 SBDFP => SBDF
SBDFP => SBDF
BPCK => GPCK
BPCK => GPCK
 SBDFP => SBDG
SBDFP => SBDF => SBDG
BPCK => IN
BPCK => GPCK => SCD => SCDC => IN
 SBDFP => SCD
SBDFP => SBD => SCD
BPCK => MIN
BPCK => GPCK => SCD => MIN
 SBDFP => SCDC
SBDFP => SBD => SCDC
BPCK => PIN
BPCK => GPCK => SCD => SCDC => PIN
 SBDFP => SCDF
SBDFP => SBDF => SCDF
BPCK => SBD
BPCK => SBD
 SBDFP => SCDFP
SBDFP => SCDFP
BPCK => SBDC
BPCK => SBD => SBDC
 SBDFP => SCDG
SBDFP => SBD => SCD => SCDG
BPCK => SBDF
BPCK => SBD => SBDF
 SBDFP => SCDGP
SBDFP => SBDF => SBDG => SCDGP
BPCK => SBDFP
BPCK => SBD => SBDFP
 SBDG => BN
SBDG => BN
BPCK => SBDG
BPCK => SBD => SBDG
 SBDG => BPCK
SBDG => SBD => BPCK
BPCK => SCD
BPCK => GPCK => SCD
 SBDG => DF
SBDG => SBD => DF
BPCK => SCDC
BPCK => GPCK => SCD => SCDC
 SBDG => DFG
SBDG => DFG
BPCK => SCDF
BPCK => GPCK => SCD => SCDF
 SBDG => GPCK
SBDG => SBD => SCD => GPCK
BPCK => SCDFP
BPCK => GPCK => SCD => SCDFP
 SBDG => IN
SBDG => BN => IN
BPCK => SCDG
BPCK => GPCK => SCD => SCDG
 SBDG => MIN
SBDG => SBD => SCD => MIN
BPCK => SCDGP
BPCK => GPCK => SCD => SCDG => SCDGP
 SBDG => PIN
SBDG => SBD => SCD => SCDC => PIN
GPCK => BN
GPCK => SCD => SBD => SBDF => BN
 SBDG => SBD
SBDG => SBD
GPCK => BPCK
GPCK => BPCK
 SBDG => SBDC
SBDG => SBD => SBDC
GPCK => DF
GPCK => DF
 SBDG => SBDF
SBDG => SBDF
GPCK => DFG
GPCK => SCD => SCDG => DFG
 SBDG => SBDFP
SBDG => SBDF => SBDFP
GPCK => IN
GPCK => SCD => SCDC => IN
 SBDG => SCD
SBDG => SBD => SCD
GPCK => MIN
GPCK => SCD => MIN
 SBDG => SCDC
SBDG => SBD => SCD => SCDC
GPCK => PIN
GPCK => SCD => SCDC => PIN
 SBDG => SCDF
SBDG => SBD => SCD => SCDF
GPCK => SBD
GPCK => SCD => SBD
 SBDG => SCDFP
SBDG => SBD => SCD => SCDFP
GPCK => SBDC
GPCK => SCD => SBD => SBDC
 SBDG => SCDG
SBDG => SCDG
GPCK => SBDF
GPCK => SCD => SBD => SBDF
 SBDG => SCDGP
SBDG => SCDGP
GPCK => SBDFP
GPCK => SCD => SBD => SBDFP
 SCD => BN
SCD => SBD => BN
GPCK => SBDG
GPCK => SCD => SBD => SBDG
 SCD => BPCK
SCD => GPCK => BPCK
GPCK => SCD
GPCK => SCD
 SCD => DF
SCD => DF
GPCK => SCDC
GPCK => SCD => SCDC
 SCD => DFG
SCD => SCDG => DFG
GPCK => SCDF
GPCK => SCD => SCDF
 SCD => GPCK
SCD => GPCK
GPCK => SCDFP
GPCK => SCD => SCDFP
 SCD => IN
SCD => SCDC => IN
GPCK => SCDG
GPCK => SCD => SCDG
 SCD => MIN
SCD => MIN
GPCK => SCDGP
GPCK => SCD => SCDG => SCDGP
 SCD => PIN
SCD => SCDC => PIN
IN => BN
IN => BN
 SCD => SBD
SCD => SBD
IN => BPCK
IN => SCDC => SCD => GPCK => BPCK
 SCD => SBDC
SCD => SBD => SBDC
IN => DF
IN => SCDC => SCD => DF
 SCD => SBDF
SCD => SBD => SBDF
IN => DFG
IN => SCDG => DFG
 SCD => SBDFP
SCD => SBD => SBDFP
IN => GPCK
IN => SCDC => SCD => GPCK
 SCD => SBDG
SCD => SBD => SBDG
IN => MIN
IN => MIN
 SCD => SCDC
SCD => SCDC
IN => PIN
IN => PIN
 SCD => SCDF
SCD => SCDF
IN => SBD
IN => BN => SBD
 SCD => SCDFP
SCD => SCDFP
IN => SBDC
IN => BN => SBDC
 SCD => SCDG
SCD => SCDG
IN => SBDF
IN => BN => SBDF
 SCD => SCDGP
SCD => SCDG => SCDGP
IN => SBDFP
IN => BN => SBDF => SBDFP
 SCDC => BN
SCDC => SBD => SBDF => BN
IN => SBDG
IN => SCDG => SBDG
 SCDC => BPCK
SCDC => SCD => GPCK => BPCK
IN => SCD
IN => SCDC => SCD
 SCDC => DF
SCDC => SCD => DF
IN => SCDC
IN => SCDC
 SCDC => DFG
SCDC => SCD => SCDG => DFG
IN => SCDF
IN => SCDF
 SCDC => GPCK
SCDC => SCD => GPCK
IN => SCDFP
IN => SCDFP
 SCDC => IN
SCDC => IN
IN => SCDG
IN => SCDG
 SCDC => MIN
SCDC => SCD => MIN
IN => SCDGP
IN => SCDFP => SCDGP
 SCDC => PIN
SCDC => PIN
MIN => BN
MIN => SCD => SBD => BN
 SCDC => SBD
SCDC => SBD
MIN => BPCK
MIN => SCD => GPCK => BPCK
 SCDC => SBDC
SCDC => SBDC
MIN => DF
MIN => SCD => DF
 SCDC => SBDF
SCDC => SBD => SBDF
MIN => DFG
MIN => SCD => SCDG => DFG
 SCDC => SBDFP
SCDC => SBD => SBDFP
MIN => GPCK
MIN => SCD => GPCK
 SCDC => SBDG
SCDC => SBD => SBDG
MIN => IN
MIN => IN
 SCDC => SCD
SCDC => SCD
MIN => PIN[2]
MIN => SCD => SCDC => PIN
 SCDC => SCDF
SCDC => SCD => SCDF
MIN => SBD
MIN => SCD => SBD
 SCDC => SCDFP
SCDC => SCD => SCDFP
MIN => SBDC
MIN => SCD => SBD => SBDC
 SCDC => SCDG
SCDC => SCD => SCDG
MIN => SBDF
MIN => SCD => SBD => SBDF
 SCDC => SCDGP
SCDC => SCD => SCDG => SCDGP
MIN => SBDFP
MIN => SCD => SBD => SBDFP
 SCDF => BN
SCDF => SBDF => BN
MIN => SBDG
MIN => SCD => SBD => SBDG
 SCDF => BPCK
SCDF => SCD => GPCK => BPCK
MIN => SCD
MIN => SCD
 SCDF => DF
SCDF => DF
MIN => SCDC
MIN => SCD => SCDC
 SCDF => DFG
SCDF => SCDG => DFG
MIN => SCDF
MIN => SCD => SCDF
 SCDF => GPCK
SCDF => SCD => GPCK
MIN => SCDFP
MIN => SCD => SCDFP
 SCDF => IN
SCDF => IN
MIN => SCDG
MIN => SCD => SCDG
 SCDF => MIN
SCDF => SCD => MIN
MIN => SCDGP
MIN => SCD => SCDG => SCDGP
 SCDF => PIN
SCDF => SCD => SCDC => PIN
PIN => BN[1]
PIN => SCDC => SBD => BN
 SCDF => SBD
SCDF => SCD => SBD
PIN => BPCK
PIN => SCDC => SCD => GPCK => BPCK
 SCDF => SBDC
SCDF => SCD => SBD => SBDC
PIN => DF
PIN => SCDC => SCD => DF
 SCDF => SBDF
SCDF => SBDF
PIN => DFG
PIN => SCDC => SCD => SCDG => DFG
 SCDF => SBDFP
SCDF => SBDF => SBDFP
PIN => GPCK
PIN => SCDC => SCD => GPCK
 SCDF => SBDG
SCDF => SCDG => SBDG
PIN => IN
PIN => IN
 SCDF => SCD
SCDF => SCD
PIN => MIN[2]
PIN => SCDC => SCD => MIN
 SCDF => SCDC
SCDF => SCD => SCDC
PIN => SBD
PIN => SCDC => SBD
 SCDF => SCDFP
SCDF => SCDFP
PIN => SBDC
PIN => SCDC => SBDC
 SCDF => SCDG
SCDF => SCDG
PIN => SBDF
PIN => SCDC => SBD => SBDF
 SCDF => SCDGP
SCDF => SCDG => SCDGP
PIN => SBDFP
PIN => SCDC => SBD => SBDFP
 SCDFP => BN
SCDFP => SCDF => SBDF => BN
PIN => SBDG
PIN => SCDC => SCD => SBD => SBDG
 SCDFP => BPCK
SCDFP => SCD => GPCK => BPCK
PIN => SCD
PIN => SCDC => SCD
 SCDFP => GPCK
SCDFP => SCD => GPCK
PIN => SCDC
PIN => SCDC
 SCDFP => IN
SCDFP => IN
PIN => SCDF
PIN => SCDC => SCD => SCDF
 SCDFP => MIN
SCDFP => SCD => MIN
PIN => SCDFP
PIN => SCDFP
 SCDFP => PIN
SCDFP => PIN
PIN => SCDG
PIN => SCDC => SCD => SCDG
 SCDFP => SBD
SCDFP => SCD => SBD
PIN => SCDGP
PIN => SCDC => SCD => SCDG => SCDGP
 SCDFP => SBDC
SCDFP => SCD => SBD => SBDC
SBD => BN
SBD => BN
 SCDFP => SBDF
SCDFP => SCDF => SBDF
SBD => BPCK
SBD => BPCK
 SCDFP => SBDFP
SCDFP => SBDFP
SBD => DF
SBD => SCD => DF
 SCDFP => SBDG
SCDFP => SCD => SBD => SBDG
SBD => DFG
SBD => SBDG => DFG
 SCDFP => SCD
SCDFP => SCD
SBD => GPCK
SBD => SCD => GPCK
 SCDFP => SCDC
SCDFP => SCD => SCDC
SBD => IN
SBD => SCDC => IN
 SCDFP => SCDF
SCDFP => SCDF
SBD => MIN
SBD => SCD => MIN
 SCDFP => SCDG
SCDFP => SCDGP => SCDG
SBD => PIN
SBD => SCDC => PIN
 SCDFP => SCDGP
SCDFP => SCDGP
SBD => SBDC
SBD => SBDC
 SCDG => BN
SCDG => SCD => SBD => BN
SBD => SBDF
SBD => SBDF
 SCDG => BPCK
SCDG => SCD => GPCK => BPCK
SBD => SBDFP
SBD => SBDFP
 SCDG => DF
SCDG => SCD => DF
SBD => SBDG
SBD => SBDG
 SCDG => DFG
SCDG => DFG
SBD => SCD
SBD => SCD
 SCDG => GPCK
SCDG => SCD => GPCK
SBD => SCDC
SBD => SCDC
 SCDG => IN
SCDG => IN
SBD => SCDF
SBD => SCD => SCDF
 SCDG => MIN
SCDG => SCD => MIN
SBD => SCDFP
SBD => SCD => SCDFP
 SCDG => PIN
SCDG => SCD => SCDC => PIN
SBD => SCDG
SBD => SCD => SCDG
 SCDG => SBD
SCDG => SCD => SBD
SBD => SCDGP
SBD => SCD => SCDG => SCDGP
 SCDG => SBDC
SCDG => SCD => SBD => SBDC
SBDC => BN
SBDC => SBD => SBDF => BN
 SCDG => SBDF
SCDG => SCD => SBD => SBDF
SBDC => BPCK
SBDC => SBD => BPCK
 SCDG => SBDFP
SCDG => SCD => SBD => SBDFP
SBDC => DF
SBDC => SBD => SCD => DF
 SCDG => SBDG
SCDG => SBDG
SBDC => DFG
SBDC => SBD => SBDG => DFG
 SCDG => SCD
SCDG => SCD
SBDC => GPCK
SBDC => SBD => SCD => GPCK
 SCDG => SCDC
SCDG => SCD => SCDC
SBDC => IN
SBDC => SCDC => IN
 SCDG => SCDF
SCDG => SCDF
SBDC => MIN
SBDC => SBD => SCD => MIN
 SCDG => SCDFP
SCDG => SCDGP => SCDFP
SBDC => PIN
SBDC => SCDC => PIN
 SCDG => SCDGP
SCDG => SCDGP
SBDC => SBD
SBDC => SBD
 SCDGP => BN
SCDGP => SBDG => BN
SBDC => SBDF
SBDC => SBD => SBDF
 SCDGP => BPCK
SCDGP => SCDG => SCD => GPCK => BPCK
SBDC => SBDFP
SBDC => SBD => SBDFP
 SCDGP => GPCK
SCDGP => SCDG => SCD => GPCK
SBDC => SBDG
SBDC => SBD => SBDG
 SCDGP => IN
SCDGP => SCDFP => IN
SBDC => SCD
SBDC => SBD => SCD
 SCDGP => MIN
SCDGP => SCDG => SCD => MIN
SBDC => SCDC
SBDC => SCDC
 SCDGP => PIN
SCDGP => SCDG => SCD => SCDC => PIN
SBDC => SCDF
SBDC => SBD => SCD => SCDF
 SCDGP => SBD
SCDGP => SCDG => SCD => SBD
SBDC => SCDFP
SBDC => SBD => SCD => SCDFP
 SCDGP => SBDC
SCDGP => SCDG => SCD => SBD => SBDC
SBDC => SCDG
SBDC => SBD => SBDG => SCDG
 SCDGP => SBDF
SCDGP => SBDG => SBDF
SBDC => SCDGP
SBDC => SBD => SCD => SCDG => SCDGP
 SCDGP => SBDFP
SCDGP => SCDG => SCD => SBD => SBDFP
SBDF => BN
SBDF => BN
 SCDGP => SBDG
SCDGP => SBDG
SBDF => BPCK
SBDF => SBD => BPCK
 SCDGP => SCD
SCDGP => SCDG => SCD
SBDF => DF
SBDF => DF
 SCDGP => SCDC
SCDGP => SCDG => SCD => SCDC
SBDF => DFG
SBDF => SBDG => DFG
 SCDGP => SCDF
SCDGP => SCDG => SCDF
SBDF => GPCK
SBDF => SBD => SCD => GPCK
 SCDGP => SCDFP
SCDGP => SCDFP
SBDF => IN
SBDF => SCDF => IN
 SCDGP => SCDG
SCDGP => SCDG

Default Paths Table Notes

[1] There is a direct path from PIN to BN, but this is not used as it results in many brands that are not linked to the PIN on the generic side.

[2] There is a direct path between MIN and PIN, but that direct path is not used because it only applies to cases where there are PINs of the same ingredient.



The RxCUI View (RxCUI Tab)

The tab labeled "RxCUI" allows the user to view the status, ingredients, features, and properties of the selected concept.

Possible statuses are:

  • Active - the concept is in the current RxNorm data set and has a non-suppressed term (SUPPRESS="N" in RXNCONSO) from the RxNorm vocabulary.
  • Obsolete - the concept is designated as obsolete (SUPRRESS="O" in RXNCONSO) in the current data set.
  • Quantified - the concept has been designated as an unquantified, non-prescribable drug (SUPPRESS="E" in RXNCONSO) in the current data set.
  • Non Current - the concept satisfies one of the following conditions:
    1. The concept exists in the current data set but has no RxNorm vocabulary terms.
    2. The concept existed in previous monthly versions but has been removed and is not remapped to any Active concepts.
  • Unknown - the RxCUI has never been present in an RxNorm monthly release
The properties include the RxNorm names, codes, attributes, and the vocabulary sources of other synonyms. A sample view is shown below.

RxNorm properties view for RxCUI=208848

The NDC View (NDC Tab)

The tab labeled "NDC" allows the user to view the National Drug Codes along with its properties for a clinical drug, clinical pack, branded drug, or branded pack. The tab will be enabled when a clinical drug, clinical pack, branded drug or branded pack concept is selected (by single-clicking on the concept). To view the NDC information for that concept, simply select the NDC tab. The default table is the current NDC. A sample table is shown below.

NDC graph example

NDC properties come from RxNorm, DailyMed (SAB=MTHSPL) in the RxNorm data set or from the FDA. The following table lists the source of the data for each column in the NDC table.

Column Title Source(s) of data
NDC9 FDA or DailyMed
NDC11 RxNorm
NDC10 FDA or DailyMed
SPL_SET_ID DailyMed
LABELER FDA or DailyMed
PACKAGING FDA or DailyMed
NDC9 PROPERTIES FDA or DailyMed

An example of NDC9 Properties

NDC properties example


A historical NDC table which contains both past and present NDC information is also available.

NDC graph example

The status column can contain the following values:
  • Indirect – indicates the NDC was associated to a different concept designated in the RxCui column.
  • Direct – indicates the NDC is/was associated with the current concept.
The start and end date columns indicate the period of time the NDC was considered active in RxNorm for the RxCui.

The RxTerms View (RxTerms Tab)

The RxTerms view in RxNav provides the RxTerms information for a clinical or branded drug. RxTerms is a drug interface terminology derived from RxNorm for prescription writing or medication history recording.

For more information on RxTerms, click here.

A sample view is shown below.

RxTerms View

Class View (Class View Tab)

The Class View contains drug class hierarchies from ATC, MED-RT, SNOMEDCT and VA. The Views menu on the left of the screen allows the selection of the class hierarchy to display. The ATC graph is selected as default.

Class Views

A sample graph with annotations is shown below. Note that there is a widget for zooming the graph as well as positioning. Also, clicking on a class node will link to RxClass for that drug class and display the drug members for that class.

ATC graph example

Interaction View (Interaction View Tab)

The Interaction View displays the list of drugs which interact with the selected RxNorm concept.
There are two different views available – DrugBank and ONCHigh – representing the two sources of drug-drug interaction information.

Note: DrugBank contains no severity information, so an “N/A” is always displayed in the severity column for that view.

A sample table is shown below.

Interaction View example