APPLICATIONS

APPLICATIONS

RxNav Overview

RxNav Views

Content

Overview

RxNav has a number of views (tabs) which display related information of the selected concept.

RxNav views (tabs) for displaying other related information

The RxNorm Graph View is the default view and displays the selected concept with its related RxNorm concepts.

The RxNorm Properties View contains the RxNorm properties related to the concept.

The NDC View displays the National Drug Code information for the concept.

The RxTerms View displays the RxTerms vocabulary information related to the concept.

The Class View displays drug class hierarchies from several drug vocabularies.

The Interaction View displays the drug interactions with the selected concept.

The Status View displays status, metadata and attributes of the selected concept.

RxNav Graph View (RxNorm Graph Tab)

The RxNorm Graph View is the default tab when RxNav is started. When the user enters RxNav, the options for the graph are displayed on the left, and the graph components to the right of the options. The default graph is the classic graph, which contains eleven tables containing the RxNorm term types.

image of RxNorm graph

After a search is done, the RxNorm graph is populated with the concept found plus the related concepts.

The concept found from the search string is highlighted. By clicking on a concept in one of the tables, that concept string becomes the search term and all of its related components will then be displayed.

To populate the display, RxNav uses a set of default paths to traverse from the starting concept term type to find related concepts of the different term types. The path table shows the default paths used for each starting term type.

Graph Types
RxNav provides a classic graph view, a simple graph view and a table view, selectable under the Views label in the options:

RxNav graph views

The simple view provides two tables, one containing the ingredients and related products, the other for brand names and related branded products. The figure below contains the simple view for the ingredient ezetimibe.

RxNav simple view

The table view provides the same information as the classic view, but in a single table. The figure below contains the table view for the brand Celexa.

RxNav table view

Graph Filters
RxNav provides filters for the classic and simple graphs:

Graph filters

The selection of a filter implies that the graph should contain only those entries. For example, selecting Human means only those drugs containing the H or HV icon are selected for the graph. Selecting Human and Vet will result in only those drugs displaying the HV icon are selected. Similarly, selection of the prescribable filter (Rx icon) will eliminate non-prescribable concepts from the graph.

Group or Form Display
For the classic view, the user has the option of selecting either Group Term Types (default) or Form Term Types.

Group or Form TTYs

Links to other drug information

RxNav links for displaying other related information

Drug Label Link
This link provides the drug label information from DailyMed .

MedlinePlus Link
The MedlinePlus link allows users to view MedlinePlus drug information using the MedlinePlus Connect API. When the MedlinePlus link is selected, the MedlinePlus results web page is displayed.

Drug Information Button
The link labeled "Drug Portal" connects to the Drug Information Portal to provide links about related drug information from both NLM and other sources.

Other Graph Symbols
The Legend provides other symbols which occur in the RxNorm graph.

RxNav Legend

MIN icon – identifies the concept as a multiple ingredient term type (MIN)
Pack icon – identifies the concept as a Pack term type (GPCK or BPCK)
Multi icon – identifies the concept as containing multiple ingredients

Download Button
The download button copies the information in the graph to a file with comma separated fields.
Download button

Default Paths

The default path table below shows the paths through the term types that are taken by RxNav to display the related concepts. (Note: these are also the paths used by the RxNorm API in the functions getAllRelatedInfo and getRelatedByType.)

The first and third columns indicate the starting term type associated with the selected identifier and the ending term type.
The second and fourth columns are the list of term types in order (the path) to get the related concepts of the ending term type from the starting term type.
Abbreviations
  BN - brand name     SBD - branded drug
  BPCK - branded pack     SBDC - branded drug component
  DF - dose form     SBDF - branded dose form
  DFG - dose form group     SBDG - branded dose form group
  GPCK - generic pack     SCD - clinical drug
  IN - ingredient     SCDC - clinical drug component
  MIN - multiple ingredients     SCDF - clinical dose form
  PIN - precise ingredient     SCDG - clinical dose form group


Default Paths
Start to End Path Start to End Path
BN => BPCK
BN => SBD => BPCK
 SBDC => BN
SBDC => SBD => SBDF => BN
BN => DF
BN => SBD => SCD => DF
 SBDC => BPCK
SBDC => SBD => BPCK
BN => DFG
BN => SBD => SBDG => DFG
 SBDC => DF
SBDC => SBD => SCD => DF
BN => GPCK
BN => SBD => SCD => GPCK
 SBDC => DFG
SBDC => SBD => SBDG => DFG
BN => IN
BN => IN
 SBDC => GPCK
SBDC => SBD => SCD => GPCK
BN => MIN
BN => SBD => SCD => MIN
 SBDC => IN
SBDC => SCDC => IN
BN => PIN[1]
BN => PIN
 SBDC => MIN
SBDC => SBD => SCD => MIN
BN => SBD
BN => SBD
 SBDC => PIN
SBDC => SCDC => PIN
BN => SBDC
BN => SBDC
 SBDC => SBD
SBDC => SBD
BN => SBDF
BN => SBDF
 SBDC => SBDF
SBDC => SBD => SBDF
BN => SBDG
BN => SBDG
 SBDC => SBDG
SBDC => SBD => SBDG
BN => SCD
BN => SBD => SCD
 SBDC => SCD
SBDC => SBD => SCD
BN => SCDC
BN => SBDC => SCDC
 SBDC => SCDC
SBDC => SCDC
BN => SCDF
BN => SBDF => SCDF
 SBDC => SCDF
SBDC => SBD => SCD => SCDF
BN => SCDG
BN => SBDG => SCDG
 SBDC => SCDG
SBDC => SBD => SBDG => SCDG
BPCK => BN
BPCK => SBD => SBDF => BN
 SBDF => BN
SBDF => BN
BPCK => DF
BPCK => DF
 SBDF => BPCK
SBDF => SBD => BPCK
BPCK => DFG
BPCK => GPCK => SCD => SCDG => DFG
 SBDF => DF
SBDF => DF
BPCK => GPCK
BPCK => GPCK
 SBDF => DFG
SBDF => SBDG => DFG
BPCK => IN
BPCK => GPCK => SCD => SCDC => IN
 SBDF => GPCK
SBDF => SBD => SCD => GPCK
BPCK => MIN
BPCK => GPCK => SCD => MIN
 SBDF => IN
SBDF => SCDF => IN
BPCK => PIN
BPCK => GPCK => SCD => SCDC => PIN
 SBDF => MIN
SBDF => SBD => SCD => MIN
BPCK => SBD
BPCK => SBD
 SBDF => PIN
SBDF => SBD => SCDC => PIN
BPCK => SBDC
BPCK => SBD => SBDC
 SBDF => SBD
SBDF => SBD
BPCK => SBDF
BPCK => SBD => SBDF
 SBDF => SBDC
SBDF => SBD => SBDC
BPCK => SBDG
BPCK => SBD => SBDG
 SBDF => SBDG
SBDF => SBDG
BPCK => SCD
BPCK => GPCK => SCD
 SBDF => SCD
SBDF => SBD => SCD
BPCK => SCDC
BPCK => GPCK => SCD => SCDC
 SBDF => SCDC
SBDF => SBD => SCD => SCDC
BPCK => SCDF
BPCK => GPCK => SCD => SCDF
 SBDF => SCDF
SBDF => SCDF
BPCK => SCDG
BPCK => GPCK => SCD => SCDG
 SBDF => SCDG
SBDF => SBDG => SCDG
GPCK => BN
GPCK => SCD => SBD => SBDF => BN
 SBDG => BN
SBDG => BN
GPCK => BPCK
GPCK => BPCK
 SBDG => BPCK
SBDG => SBD => BPCK
GPCK => DF
GPCK => DF
 SBDG => DF
SBDG => SBD => DF
GPCK => DFG
GPCK => SCD => SCDG => DFG
 SBDG => DFG
SBDG => DFG
GPCK => IN
GPCK => SCD => SCDC => IN
 SBDG => GPCK
SBDG => SBD => SCD => GPCK
GPCK => MIN
GPCK => SCD => MIN
 SBDG => IN
SBDG => BN => IN
GPCK => PIN
GPCK => SCD => SCDC => PIN
 SBDG => MIN
SBDG => SBD => SCD => MIN
GPCK => SBD
GPCK => SCD => SBD
 SBDG => PIN
SBDG => SBD => SCD => SCDC => PIN
GPCK => SBDC
GPCK => SCD => SBD => SBDC
 SBDG => SBD
SBDG => SBD
GPCK => SBDF
GPCK => SCD => SBD => SBDF
 SBDG => SBDC
SBDG => SBD => SBDC
GPCK => SBDG
GPCK => SCD => SBD => SBDG
 SBDG => SBDF
SBDG => SBDF
GPCK => SCD
GPCK => SCD
 SBDG => SCD
SBDG => SBD => SCD
GPCK => SCDC
GPCK => SCD => SCDC
 SBDG => SCDC
SBDG => SBD => SCD => SCDC
GPCK => SCDF
GPCK => SCD => SCDF
 SBDG => SCDF
SBDG => SBD => SCD => SCDF
GPCK => SCDG
GPCK => SCD => SCDG
 SBDG => SCDG
SBDG => SCDG
IN => BN
IN => BN
 SCD => BN
SCD => SBD => BN
IN => BPCK
IN => SCDC => SCD => GPCK => BPCK
 SCD => BPCK
SCD => GPCK => BPCK
IN => DF
IN => SCDC => SCD => DF
 SCD => DF
SCD => DF
IN => DFG
IN => SCDG => DFG
 SCD => DFG
SCD => SCDG => DFG
IN => GPCK
IN => SCDC => SCD => GPCK
 SCD => GPCK
SCD => GPCK
IN => MIN
IN => MIN
 SCD => IN
SCD => SCDC => IN
IN => PIN
IN => PIN
 SCD => MIN
SCD => MIN
IN => SBD
IN => BN => SBD
 SCD => PIN
SCD => SCDC => PIN
IN => SBDC
IN => BN => SBDC
 SCD => SBD
SCD => SBD
IN => SBDF
IN => BN => SBDF
 SCD => SBDC
SCD => SBD => SBDC
IN => SBDG
IN => SCDG => SBDG
 SCD => SBDF
SCD => SBD => SBDF
IN => SCD
IN => SCDC => SCD
 SCD => SBDG
SCD => SBD => SBDG
IN => SCDC
IN => SCDC
 SCD => SCDC
SCD => SCDC
IN => SCDF
IN => SCDF
 SCD => SCDF
SCD => SCDF
IN => SCDG
IN => SCDG
 SCD => SCDG
SCD => SCDG
MIN => BN
MIN => SCD => SBD => BN
 SCDC => BN
SCDC => SBD => SBDF => BN
MIN => BPCK
MIN => SCD => GPCK => BPCK
 SCDC => BPCK
SCDC => SCD => GPCK => BPCK
MIN => DF
MIN => SCD => DF
 SCDC => DF
SCDC => SCD => DF
MIN => DFG
MIN => SCD => SCDG => DFG
 SCDC => DFG
SCDC => SCD => SCDG => DFG
MIN => GPCK
MIN => SCD => GPCK
 SCDC => GPCK
SCDC => SCD => GPCK
MIN => IN
MIN => IN
 SCDC => IN
SCDC => IN
MIN => PIN[2]
MIN => SCD => SCDC => PIN
 SCDC => MIN
SCDC => SCD => MIN
MIN => SBD
MIN => SCD => SBD
 SCDC => PIN
SCDC => PIN
MIN => SBDC
MIN => SCD => SBD => SBDC
 SCDC => SBD
SCDC => SBD
MIN => SBDF
MIN => SCD => SBD => SBDF
 SCDC => SBDC
SCDC => SBDC
MIN => SBDG
MIN => SCD => SBD => SBDG
 SCDC => SBDF
SCDC => SBD => SBDF
MIN => SCD
MIN => SCD
 SCDC => SBDG
SCDC => SBD => SBDG
MIN => SCDC
MIN => SCD => SCDC
 SCDC => SCD
SCDC => SCD
MIN => SCDF
MIN => SCD => SCDF
 SCDC => SCDF
SCDC => SCD => SCDF
MIN => SCDG
MIN => SCD => SCDG
 SCDC => SCDG
SCDC => SCD => SCDG
PIN => BN[1]
PIN => SCDC => SBD => BN
 SCDF => BN
SCDF => SBDF => BN
PIN => BPCK
PIN => SCDC => SCD => GPCK => BPCK
 SCDF => BPCK
SCDF => SCD => GPCK => BPCK
PIN => DF
PIN => SCDC => SCD => DF
 SCDF => DF
SCDF => DF
PIN => DFG
PIN => SCDC => SCD => SCDG => DFG
 SCDF => DFG
SCDF => SCDG => DFG
PIN => GPCK
PIN => SCDC => SCD => GPCK
 SCDF => GPCK
SCDF => SCD => GPCK
PIN => IN
PIN => IN
 SCDF => IN
SCDF => IN
PIN => MIN[2]
PIN => SCDC => SCD => MIN
 SCDF => MIN
SCDF => SCD => MIN
PIN => SBD
PIN => SCDC => SBD
 SCDF => PIN
SCDF => SCD => SCDC => PIN
PIN => SBDC
PIN => SCDC => SBDC
 SCDF => SBD
SCDF => SCD => SBD
PIN => SBDF
PIN => SCDC => SBD => SBDF
 SCDF => SBDC
SCDF => SCD => SBD => SBDC
PIN => SBDG
PIN => SCDC => SCD => SBD => SBDG
 SCDF => SBDF
SCDF => SBDF
PIN => SCD
PIN => SCDC => SCD
 SCDF => SBDG
SCDF => SCDG => SBDG
PIN => SCDC
PIN => SCDC
 SCDF => SCD
SCDF => SCD
PIN => SCDF
PIN => SCDC => SCD => SCDF
 SCDF => SCDC
SCDF => SCD => SCDC
PIN => SCDG
PIN => SCDC => SCD => SCDG
 SCDF => SCDG
SCDF => SCDG
SBD => BN
SBD => BN
 SCDG => BN
SCDG => SCD => SBD => BN
SBD => BPCK
SBD => BPCK
 SCDG => BPCK
SCDG => SCD => GPCK => BPCK
SBD => DF
SBD => SCD => DF
 SCDG => DF
SCDG => SCD => DF
SBD => DFG
SBD => SBDG => DFG
 SCDG => DFG
SCDG => DFG
SBD => GPCK
SBD => SCD => GPCK
 SCDG => GPCK
SCDG => SCD => GPCK
SBD => IN
SBD => SCDC => IN
 SCDG => IN
SCDG => IN
SBD => MIN
SBD => SCD => MIN
 SCDG => MIN
SCDG => SCD => MIN
SBD => PIN
SBD => SCDC => PIN
 SCDG => PIN
SCDG => SCD => SCDC => PIN
SBD => SBDC
SBD => SBDC
 SCDG => SBD
SCDG => SCD => SBD
SBD => SBDF
SBD => SBDF
 SCDG => SBDC
SCDG => SCD => SBD => SBDC
SBD => SBDG
SBD => SBDG
 SCDG => SBDF
SCDG => SCD => SBD => SBDF
SBD => SCD
SBD => SCD
 SCDG => SBDG
SCDG => SBDG
SBD => SCDC
SBD => SCDC
 SCDG => SCD
SCDG => SCD
SBD => SCDF
SBD => SCD => SCDF
 SCDG => SCDC
SCDG => SCD => SCDC
SBD => SCDG
SBD => SCD => SCDG
 SCDG => SCDF
SCDG => SCDF

Default Paths Table Notes

[1] There is a direct path from PIN to BN, but this is not used as it results in many brands that are not linked to the PIN on the generic side.

[2] There is a direct path between MIN and PIN, but that direct path is not used because it only applies to cases where there are PINs of the same ingredient.



The RxNorm Properties View (RxNorm Properties Tab)

The tab labeled "RxNorm Properties" allows the user to view the RxNorm properties for the selected concept. These properties include the RxNorm names, codes, attributes, and the vocabulary sources of other synonyms. A sample view is shown below.

RxNorm properties view for RxCUI=208848

The NDC View (NDC Tab)

The tab labeled "NDC" allows the user to view the National Drug Codes along with its properties for a clinical drug, clinical pack, branded drug or branded pack. The tab will be enabled when a clinical drug, clinical pack, branded drug or branded pack concept is selected ( by single-clicking on the concept). To view the NDC information for that concept, simply select the NDC tab. The default table is the current NDC. A sample table is shown below.

NDC graph example

NDC properties come from RxNorm, DailyMed (SAB=MTHSPL) in the RxNorm data set or from the FDA. The following table lists the source of the data for each column in the NDC table.

Column Title Source(s) of data
NDC9 FDA or DailyMed
NDC11 RxNorm
NDC10 FDA or DailyMed
SPL_SET_ID DailyMed
LABELER FDA or DailyMed
PACKAGING FDA or DailyMed
NDC9 PROPERTIES FDA or DailyMed

An example of NDC9 Properties

NDC properties example


A historical NDC table which contains both past and present NDC information is also available.

NDC graph example

The status column can contain the following values:
  • Indirect – indicates the NDC was associated to a different concept designated in the RxCui column.
  • Direct – indicates the NDC is/was associated with the current concept.
The start and end date columns indicate the period of time the NDC was considered active in RxNorm for the RxCui.

The RxTerms View (RxTerms Tab)

The RxTerms view in RxNav provides the RxTerms information for a clinical or branded drug. RxTerms is a drug interface terminology derived from RxNorm for prescription writing or medication history recording.

For more information on RxTerms, click here.

A sample view is shown below.

RxTerms View

Class View (Class View Tab)

The Class View contains drug class hierarchies from ATC, MeSH, MED-RT, SNOMEDCT and VA. The Views menu on the left of the screen allows the selection of the class hierarchy to display. The ATC graph is selected as default.

Class Views

A sample graph with annotations is shown below. Note that there is a widget for zooming the graph as well as positioning. Also, clicking on a class node will link to RxClass for that drug class and display the drug members for that class.

ATC graph example

Interaction View (Interaction View Tab)

The Interaction View displays the list of drugs which interact with the selected RxNorm concept.
There are two different views available – DrugBank and ONCHigh – representing the two sources of drug-drug interaction information.

Note: DrugBank contains no severity information, so an “N/A” is always displayed in the severity column for that view.

A sample table is shown below.

Interaction View example

Status View (Status View Tab)

The Status View displays status, ingredients, and metadata of the selected concept. Possible statuses are:
  • Active (green) - the concept is in the current RxNorm data set and has a non-suppressed term (SUPPRESS="N" in RXNCONSO) from the RxNorm vocabulary.
  • Obsolete (yellow) - the concept is designated as obsolete (SUPRRESS="O" in RXNCONSO) in the current data set.
  • Quantified (orange) - the concept has been designated as an unquantified, non-prescribable drug (SUPPRESS="E" in RXNCONSO) in the current data set.
  • Non Current (red) - the concept satisfies one of the following conditions:
    1. The concept exists in the current data set but has no RxNorm vocabulary terms.
    2. The concept existed in previous monthly versions but has been removed and is not remapped to any Active concepts.
  • Not Found (white) – the RxCUI has never been present in an RxNorm monthly release.

An active example is shown below.

Interaction View example