The RxClass Browser is a web application for exploring and navigating through the class hierarchies to find the RxNorm drug members associated with each class.
The RxClass API is available for users to include RxClass data in their applications.
RxClass links drug classes with several drug sources to their RxNorm drug members (usually ingredients, precise ingredients and multiple ingredients).
RxClass allows users to search by class name or identifier to find the RxNorm drug members or, conversely, search by RxNorm drug name or identifier to find the classes that the RxNorm drug is a member of.
|Note: In June 2018, NDF-RT was replaced by MED-RT as a source of drug class relations. Additionally, the VA drug-class relations contained in NDF-RT were replaced by VANDF data.|
SNOMED CT® Usage Conditions
RxClass includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO). All rights reserved. SNOMED CT® was originally created by the College of American Pathologists. “SNOMED”, “SNOMED CT” and “SNOMED Clinical Terms” are registered trademarks of the IHTSDO.
Use of SNOMED CT in RxClass is subject to the SNOMED CT Affiliate license provisions (incorporated in the License Agreement for Use of the UMLS Metathesaurus as Appendix 2) issued by the National Library of Medicine on behalf of SNOMED International.
|Note: the three sources - DailyMed, MEDRT and FDASPL - contain overlapping and redundant associations of drugs to some of the class trees (see tables below), so to avoid confusion only one of those sources is selected at any given time in RxClass.|
|Class \ Source||ATC||DailyMed||FDASPL||FMTSME||MEDRT||MeSH||RXNORM||SNOMEDCT|| VA|
|Drug Source||Relation||Drug Class||Description|
|ATC (level 5)||ATC1-4||Drug members of an ATC class|
|DailyMed||has_EPC||EPC||Drug members of a FDA Established Pharmacologic Class|
|DailyMed||has_Chemical_Structure||Chem||Drugs that have a chemical structure|
|DailyMed||has_MoA||MoA||Drugs that have a Mechanism of Action|
|DailyMed||has_PE||PE||Drugs that have a Physiologic Effect|
|FDASPL||has_EPC||EPC||Drug members of a FDA Established Pharmacologic Class|
|FDASPL||has_Chemical_Structure||Chem||Drugs that have a chemical structure|
|FDASPL||has_MoA||MoA||Drugs that have a Mechanism of Action|
|FDASPL||has_PE||PE||Drugs that have a Physiologic Effect|
|FMTSME||has_TC||TC||Drugs that have Therapeutic Categories|
|MEDRT||CI_ChemClass||Chem||Drugs that are contraindicated with a chemical class|
|MEDRT||has_ingredient||Chem||Drugs that are members of a chemical class|
|MEDRT||has_active_metabolites||Chem||Drugs that have active metabolites in a chemical class|
|MEDRT||CI_with||Disease||Drugs that are contraindicated with a disease|
|MEDRT||induces||Disease||Drugs that induce a disease|
|MEDRT||may_diagnose||Disease||Drugs that may diagnose a disease|
|MEDRT||may_prevent||Disease||Drugs that may prevent a disease|
|MEDRT||may_treat||Disease||Drugs that may treat a disease|
|MEDRT||CI_MoA||MoA||Drugs that are contraindicated with a Mechanism of Action|
|MEDRT||has_MoA||MoA||Drugs that have a Mechanism of Action|
|MEDRT||CI_PE||PE||Drugs that are contraindicated with a Physologic Effect|
|MEDRT||has_PE||PE||Drugs that have a Physiologic Effect|
|MEDRT||has_PK||PK||Drugs that are members of a Pharmacokinetics Class|
|MEDRT||site_of_metabolism||PK||Drugs that have a site of metabolism in a Pharmacokinetics Class|
|MeSH||MeshPA||Drug members of a MeSH Pharmacologic Action|
|RXNORM||has_schedule||Schedule||Drugs that are considered controlled substances under the Controlled Substances Act (CSA)|
|SNOMEDCT||isa_disposition||Disposition||Drugs that have a "disposition" (e.g., mechanism of action)|
|SNOMEDCT||isa_structure||Structure||Drugs that have a chemical structure|
|VA||has_VAClass||VA||Clinical drugs that are members of a VA Class|
|VA||has_VAClass_extended||VA||Related clinical and branded drugs that are derived members of a VA Class. For example, branded drugs related to clinical drugs that are mapped to a VA class, or clinical drugs that have a different dosages from ones that are mapped to a VA class.|