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<br><pre><b>The neighbours are:</b></pre><hr>
(1)
97.027 Rosenbaum JL, Almli CR, Yundt KD, Altman DI, Powers WJ<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9339686">9339686</A>
Higher neonatal cerebral blood flow correlates with worse childhood neurologic outcome.<hr>
(2)
33.9859 Altman DI, Powers WJ, Perlman JM, Herscovitch P, Volpe SL, Volpe JJ<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3263081">3263081</A>
Cerebral blood flow requirement for brain viability in newborn infants is lower than in adults.<hr>
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(20)
24.6715 Bednarczyk EM, Rutherford WF, Leisure GP, Munger MA, Panacek EA, Miraldi FD, Green JA<br>
<A href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2343589">2343589</A>
UI - 97479605 PMID- 9339686 DA - 19971114 DCOM- 19971114 LR - 20001218 IS - 0028-3878 VI - 49 IP - 4 DP - 1997 Oct TI - Higher neonatal cerebral blood flow correlates with worse childhood neurologic outcome. PG - 1035-41 AB - Cerebral blood flow (CBF) in newborn infants is often below levels necessary to sustain brain viability in adults. Controversy exists regarding the effects of such low CBF on subsequent neurologic function. We determined the current childhood neurologic status and IQ in 26 subjects who had measurements of CBF performed with PET in the neonatal period between 1983 and 1989 as part of a study of hypoxic-ischemic encephalopathy. Follow-up information at ages 4 to 12 years was obtained on all 26 subjects. Ten subjects had died. All 16 survivors underwent clinical neurologic evaluation, and 14 also underwent intelligence testing. Eight had abnormal clinical neurologic evaluations; eight were normal. The mean neonatal CBF in those with abnormal childhood neurologic outcome was significantly higher than in those with normal childhood neurologic outcome (35.64 +/- 11.80 versus 18.26 +/- 8.62 mL 100 g(-1) min(-1), t = 3.36, p = 0.005). A significant negative correlation between neonatal CBF and childhood IQ was demonstrated (Spearman rank correlation r = -0.675, p = 0.008). Higher CBF was associated with lower IQ. The higher CBF in subjects with worse neurologic and intellectual outcome may reflect greater loss of cerebrovascular autoregulation or other vascular regulatory mechanisms due to more severe brain damage. AD - Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, MO 63110, USA. AU - Rosenbaum JL AU - Almli CR AU - Yundt KD AU - Altman DI AU - Powers WJ LA - eng ID - NS06833/NS/NINDS ID - NS32568/NS/NINDS PT - Journal Article CY - UNITED STATES TA - Neurology JC - NZ0 JID - 0401060 SB - AIM SB - IM MH - Cerebrovascular Circulation/*physiology MH - *Child Development MH - Follow-Up Studies MH - Human MH - Infant, Newborn MH - Intelligence MH - *Nervous System Physiology MH - Neurologic Examination MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Tomography, Emission-Computed EDAT- 1997/10/27 20:29 MHDA- 1997/10/27 20:29 PST - ppublish SO - Neurology 1997 Oct;49(4):1035-41.
97479605|IM|Brain|33.9859 97479605|IM|Brain Diseases|33.9859 97479605|IM|Cerebrovascular Circulation|33.9859 97479605|NIM|Gestational Age|33.9859 97479605|NIM|Infant, Premature|33.9859 97479605|IM|Tomography, Emission-Computed|33.9859 *** 97479605|NIM|Asphyxia Neonatorum|29.0115
97479605|IM|Brain|29.0115
97479605|IM|Brain Ischemia|29.0115
97479605|IM|Cerebrovascular Circulation|29.0115
97479605|IM|Hypoxia, Brain|29.0115
97479605|IM|Intracranial Pressure|29.0115
97479605|IM|Oxygen|29.0115
97479605|NIM|Prognosis|29.0115 *** ... ***
97479605|IM|Cerebrovascular Circulation|24.6715
97479605|NIM|Hypercapnia|24.6715
97479605|IM|Hyperventilation|24.6715
97479605|NIM|Oxygen Radioisotopes|24.6715
97479605|NIM|Tomography, Emission-Computed|24.6715 ***