Zhiyun Xue, PhD

Computational Health Research Branch

Contact Information
Building 38A - Lister Hill Center, 10S1008

Expertise and Research Interests:

Dr. Zhiyun (Jaylene) Xue is a Staff Scientist at the Lister Hill National Center for Biomedical Communications (LHC) at the National Library of Medicine (NLM). She obtained her Ph.D. from Lehigh University USA, M.S. and B.S. from Tsinghua University, China. Dr. Xue has been working at LHC since 2006 on a number of medical imaging informatics projects. By applying her knowledge and expertise in the fields of machine learning, image processing, and computer vision to analyze biomedical images in different modalities, Dr. Xue puts her R&D efforts in those projects with the goals of advancing the research in biomedical informatics and data science, assisting clinicians at the point-of-care, improving the health of the people, and addressing the needs of the underserved population. One project she is passionate about and is currently devoting herself to is the project of automatic image analysis for cervical cancer screening, which aims to reduce the mortality of cervical cancer, one of the most common cancers among women.

Honors and Awards:

Dr. Xue received the HHS Ignite Group Award in 2014, the NLM Special Acts/Services Group Award in 2011-2014 and 2017-2019.


Angara S, Guo P, Xue Z, Antani S. Semi-Supervised Learning for Cervical Precancer Detection. 2021 IEEE 34th International Symposium on Computer-Based Medical Systems (CBMS), 2021, pp. 202-206, doi: 10.1109/CBMS52027.2021.00072.

Xue Z, Guo P, Desai K, Pal A, Ajenifuja KO, Adepiti CA, Long LR, Schiffman M, Antani S. A Deep Clustering Method for Analyzing Uterine Cervix Images Across Imaging Devices. 34th IEEE International Symposium on Computer-Based Medical Systems (CBMS), June 2021, pp. 527-532, doi: 10.1109/CBMS52027.2021.00085.

Guo P, Xue Z, Jeronimo J, Gage JC, Desai KT, Befano B, García F, Long LR, Schiffman M, Antani S. Network Visualization and Pyramidal Feature Comparison for Ablative Treatability Classification Using Digitized Cervix Images. J Clin Med. 2021 Mar 1;10(5):953. doi: 10.3390/jcm10050953.

Desai KT, Ajenifuja KO, Banjo A, Adepiti CA, Novetsky A, Sebag C, Einstein MH, Oyinloye T, Litwin TR, Horning M, Olanrewaju FO, Oripelaye MM, Afolabi E, Odujoko OO, Castle PE, Antani S, Wilson B, Hu L, Mehanian C, Demarco M, Gage JC, Xue Z, Long LR, Cheung L, Egemen D, Wentzensen N, Schiffman M. Design and feasibility of a novel program of cervical screening in Nigeria: self-sampled HPV testing paired with visual triage. Infect Agent Cancer. 2020 Oct 14;15:60. doi: 10.1186/s13027-020-00324-5.