Expertise and Research Interests:

Dr. Huser was born in the Czech republic. He received his MD from Palacky University (Olomouc, Czech republic, EU) and PhD degree in Biomedical Informatics from University of Utah (Salt Lake City, Utah, USA). His research interests are clinical informatics, knowledge representation, clinical research informatics, data repositories and data analysis, workflow technology, executable clinical guidelines, medical decision support systems and quality improvement in healthcare. As informatician, Dr. Huser worked with numerous informatics systems at Intermountain Healthcare in Utah, Marshfield Clinic in Wisconsin or NIH in Maryland (intramural campus). He is a former Fulbright scholar (his PhD degree), recipient of Young Investigator Award from HMO Research Network and has authored papers that won AMIA Distinguished paper and AMIA Homer Warner Best Paper awards.

Publications:

Fung KW, Baik SH, Baye F, Zheng Z, Huser V, McDonald CJ. Effect of common maintenance drugs on the risk and severity of COVID-19 in elderly patients. PLoS ONE 17(4): e0266922. https://doi.org/10.1371/journal.pone.0266922.

Duarte-Salles T, Vizcaya D, Pistillo A, Casajust P, Sena AG, Lai LYH, Prats-Uribe A, Ahmed W-U-R, Alshammari TM, Alghoul H, Alser O, Burn E, You SC, Areia C, Blacketer C, DuVall S, Falconer T, Fernandez-Bertolin S, Fortin S, Golozar A, Gong M, Tan EH, Huser V, Iveli P, Morales DR, Nyberg F, Posada J. 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience. Pediatrics September 2021, 148 (3) e2020042929; DOI: https://doi.org/10.1542/peds.2020-042929.

Huser V, Williams ND, Mayer CS. Linking provider specialty and outpatient diagnoses in Medicare claims data: Data quality implications. Appl Clin Inform. 2021 Aug;12(4):729-736. doi: 10.1055/s-0041-1732404.

Mayer CS, Williams N, Huser V. CONSIDER Statement: Consolidated Recommendations for Sharing Individual Participant Data from Human Clinical Studies. AMIA Annu Symp Proc. 2021;2021:438-444.

Williams N, Mayer CS, Huser V. Data Characterization of Medicaid: Legacy and New Data Formats in the CMS Virtual Research Data Center. AMIA Annu Symp Proc. 2021;2021:644-652.

Williams ND, Huser V, Rhame F, Mayer CS, Fung KW. The changing patterns of comorbidities associated with human immunodeficiency virus infection, a longitudinal retrospective cohort study of Medicare patients. Medicine (Baltimore). 2021;100(16):e25428. doi:10.1097/MD.0000000000025428.

Wilson P, Huser V. Discoverability of Information on Clinical Trial Data Sharing Platforms. J Med Libr Assoc. 2021 Apr 1;109(2):240-247. doi: 10.5195/jmla.2021.992.

Baik S, Lau J, Huser V, McDonald CJ. Association between tendon ruptures and use of fluoroquinolone, and other oral antibiotics: A 10-year retrospective study of 1 million US senior Medicare beneficiaries. BMJ Open 2020;10:34844. https://doi.org/10.1136/bmjopen-2019-034844.

Mayer CS, Huser V. Computerized monitoring of COVID-19 trials, studies and registries in ClinicalTrials.gov registry. PeerJ. 2020 Oct 23;8:e10261. doi: 10.7717/peerj.10261.

Mayer CS, Williams N, Huser V. Analysis of data dictionary formats of HIV clinical trials. PLoS One. 2020 Oct 5;15(10):e0240047. doi: 10.1371/journal.pone.0240047.

Mayer CS, Williams N, Fung KW, Huser V. Evaluation of Research Accessibility and Data Elements of HIV Registries. Curr HIV Res. 2019;17(4):258-265. doi: 10.2174/1570162X17666190924195439.

Janakiram C, Fontelo P, Huser V, Chalmers NI, Lopez Mitnik G, Brow AR, Iafolla TJ, Dye BA. Opioid Prescriptions for Acute and Chronic Pain Management Among Medicaid Beneficiaries. Am J Prev Med; 2019 09 31; 57(3):365-373. PubMed ID: 31377093.

Janakiram C, Chalmers NI, Fontelo P, Huser V, Mitnik GL, Iafolla TJ, Brow AR, Dye BA. Sex and race or ethnicity disparities in opioid prescriptions for dental diagnoses among patients receiving Medicaid. J Am Dent Assoc; 2019 Oct; 150(10):e135-e144. PMID 31561765.

Mayer CS, Williams N, Gold S, Fung KW, Huser V. Sharing of Individual Participant Data from Clinical Trials: General Comparison and HIV Use Case. AMIA Annu Symp Proc. 2020 Mar 4;2019:647-654.

Huser V, Shmueli-Blumberg D. Data sharing platforms for de-identified data from human clinical trials. Clin Trials. 2018 Aug;15(4):413-423. doi: 10.1177/1740774518769655.

Janakiram C, Chalmers NI, Fontelo P, Huser V, Lopez Mitnik GL, Iafolla TJ, Brow AR, Dye BA. Gender and Race/ethnic Disparities in Opioid Prescriptions for Dental Diagnoses among Patients with Medicaid. J Am Dent Assoc, 2018. 149(4): p. 246-255.

Huser V, Kahn MG, Brown JS, Gouripeddi R. Methods for examining data quality in healthcare integrated data repositories. Pac Symp Biocomput. 2018;23:628-633.

Bhupatiraju R, Huser V, Fung K. Phenotype modelling tools utilizing standardized EHR data in a Common Data Model format [Poster]. NIH Research Festival 2017.

Chakrabarti S, Sen A, Huser V, Hruby GW, Rusanova A, Albers DJ, Weng C. An Interoperable Similarity-based Cohort Identification Method Using the OMOP Common Data Model version 5.0. J Healthc Inform Res. 2017 Jun;1(1):1-18. doi: 10.1007/s41666-017-0005-6. Epub 2017 Jun 8.

Huser V. Clinical Data Science. Technical Report to the LHNCBC Board of Scientific Counselors April 2017.

Boyce RD, Voss EA, Huser V, Evans L, Reich C, Duke JD, Tatonetti NP, Lorberbaum T, Dumontier M, Hauben M, Wallberg M. LAERTES: An open scalable architecture for linking pharmacovigilance evidence sources with clinical data. Proc International Conference on Biomedical Ontology and BioCreative (ICBO BioCreative 2016). http://icbo2016.cgrb.oregonstate.edu/node/354.

Hripcsak G, Ryan PB, Duke JD, Shah NH, Park RW, Huser V, Suchard MA, Schuemie MJ, DeFalco FJ, Perotte A, Banda JM, Reich CG, Schilling LM, Matheny ME, Meeker D, Pratt N, Madigan D. Characterizing treatment pathways at scale using the OHDSI network. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7329-36. doi: 10.1073/pnas.1510502113. Epub 2016 Jun 6.

Huser V, Cimino JJ. Impending Challenges for the Use of Big Data. Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):890-894. doi: 10.1016/j.ijrobp.2015.10.060. Epub 2015 Nov 5.

Benedict SH, Hoffman K, Martel MK, Abernethy AP, Asher AL, Capala J, Chen RC, Chera B, Couch J, Deye J, Efstathiou JA, Ford E, Fraass BA, Gabriel PE, Huser V, Kavanagh BD, Khuntia D, Marks LB, Mayo C, McNutt T, Miller RS, Moore KL, Prior F, Roelofs E, Rosenstein BS, Sloan J, Theriault A, Vikram B. Overview of the American Society for Radiation Oncology-National Institutes of Health-American Association of Physicists in Medicine Workshop 2015: Exploring Opportunities for Radiation Oncology in the Era of Big Data. Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):873-879. doi: 10.1016/j.ijrobp.2016.03.006.

Moyer E, Hagenauer M, Lesko M, Francis F, Rodriguez O, Nagarajan V, Huser V, Busby B. MetaNetVar: Pipeline for applying network analysis tools for genomic variants analysis. F1000Res. 2016 Apr 13;5:674. doi: 10.12688/f1000research.8288.1. eCollection 2016.

Hume S, Aerts J, Sarnikar S, Huser V. Current applications and future directions for the CDISC Operational Data Model standard: A methodological review. J Biomed Inform. 2016 Apr;60:352-62. doi: 10.1016/j.jbi.2016.02.016. Epub 2016 Mar 2.

Cimino JJ, Huser V. Characterization of the Context of Drug Concepts in Research Protocols: An Empiric Study to Guide Ontology Development. AMIA Annu Symp Proc. 2015 Nov 5;2015:441-7. eCollection 2015.

Kury F, Huser V, Cimino JJ. Reproducing a Prospective Clinical Study as a Computational Retrospective Study in MIMIC-II. AMIA Annu Symp Proc. 2015 Nov 5;2015:804-13. eCollection 2015.

Huser V, Sastry C, Breymaier M, Idriss A, Cimino JJ. Standardizing data exchange for clinical research protocols and case report forms: An assessment of the suitability of the Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM). J Biomed Inform. 2015 Oct;57:88-99. doi: 10.1016/j.jbi.2015.06.023. Epub 2015 Jul 15.

Hripcsak G, Duke JD, Shah NH, Reich CG, Huser V, Schuemie MJ, Suchard MA, Park RW, Wong IC, Rijnbeek PR, van der Lei J, Pratt N, Norén GN, Li YC, Stang PE, Madigan D, Ryan PB. Observational Health Data Sciences and Informatics (OHDSI): Opportunities for Observational Researchers. Stud Health Technol Inform. 2015;216:574-8.

Cimino JJ, Ayres EJ, Remennik L, Rath S, Freedman R, Beri A, Chen Y, Huser V. The National Institutes of Health's Biomedical Translational Research Information System (BTRIS): design, contents, functionality and experience to date. J Biomed Inform. 2014 Dec;52:11-27. doi: 10.1016/j.jbi.2013.11.004. Epub 2013 Nov 19.

Rodriguez L, Huser V, Bodenreider O, Cimino J. Automatic coding of Free-Text Medication Data recorded by Research Coordinators [Poster]. AMIA Annu Symp Proc 2014:1565.

Huser V, Sincan M, Cimino JJ. Developing genomic knowledge bases and databases to support clinical management: current perspectives. Pharmgenomics Pers Med. 2014 Sep 9;7:275-83. doi: 10.2147/PGPM.S49904. eCollection 2014.

Boyce RD, Ryan PB, Noren GN, Schuemie MJ, Reich C, Duke J, Tatonetti NP, Trifiro G, Harpaz R, Overhage JM, Hartzema AG, Kayter M, Voss EA, Lambert CG, Huser V, Dumontier M. Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest. Drug Saf. 2014 Aug;37(8):557-67. doi: 10.1007/s40264-014-0189-0.

Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, Crews KR, Scott SA, , Wadelius M, Swen JJ, Tyndale RF, Stein CM, Roden D, Relling MV, Williams MS, Johnson SG. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab. 2014 Feb;15(2):209-17.

Huser V, Cimino JJ. Don't take your EHR to heaven, donate it to science: legal and research policies for EHR post mortem. J Am Med Inform Assoc. 2014 Jan-Feb;21(1):8-12. doi: 10.1136/amiajnl-2013-002061. Epub 2013 Aug 21.

Huser V, Cimino JJ. Desiderata for healthcare integrated data repositories based on architectural comparison of three public repositories. AMIA Annu Symp Proc. 2013 Nov 16;2013:648-56. eCollection 2013.

Huser V, Cimino JJ. Linking ClinicalTrials.gov and PubMed to track results of interventional human clinical trials. PLoS One. 2013 Jul 9;8(7):e68409. doi: 10.1371/journal.pone.0068409. Print 2013.

Huser V, Cimino JJ. Evaluating adherence to the International Committee of Medical Journal Editors' policy of mandatory, timely clinical trial registration. J Am Med Inform Assoc. 2013 Jun;20(e1):e169-74. doi: 10.1136/amiajnl-2012-001501. Epub 2013 Feb 9.

Kawamoto K, Jacobs J, Welch BM, Huser V, Paterno MD, Del Fiol G, Shields D, Strasberg HR, Huag PJ, Liu Z, Jenders RA, Rowed DW, Chertcoff D, Fehre K, Adlassnig KP, Curtis C. Clinical information system services and capabilities desired for scalable, standards-based, service-oriented decision support: consensus assessment of the Health Level 7 clinical decision support Work Group. AMIA Annu Symp Proc. 2012;2012:446-55. Epub 2012 Nov 3.

Huser V, Cimino JJ. Precision and negative predictive value of links between ClinicalTrials.gov and PubMed. AMIA Annu Symp Proc. 2012;2012:400-8. Epub 2012 Nov 3.

Huser V, Taft L, Cimino J. Suitability of LOINC document ontology as a reference terminology for clinical document types: a case report of a research-oriented EHR. NIH Poster Day 2012.

Del Fiol G, Huser V, Strasberg HR, Maviglia SM, Curtis C, Cimino JJ. Implementations of the HL7 Context-Aware Knowledge Retrieval ("Infobutton") Standard: challenges, strengths, limitations, and uptake. J Biomed Inform. 2012 Aug;45(4):726-35. doi: 10.1016/j.jbi.2011.12.006.. Epub 2012 Jan 2.