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Medical Ontology Research

The LHNCBC Medical Ontology Research project encompasses basic research on biomedical terminologies and ontologies and their applications to natural language processing, clinical decision support, translational medicine, data integration and interoperability. In the past few years, our research has focused on the integration, dissemination, quality assurance and applications of drug ontologies (add link to the 2014 BoSC report) and on quality assurance in biomedical ontologies. We also develop application programming interfaces (APIs) and browsers for drug resources including RxNorm, RxTerms, NDF-RT and ATC.

Publications/Tools: 
Botti G, Bodenreider O, Burgun A, Le Beux P, Fieschi M. De la Classification à la Connaissance des Maladies: Une Réflexion à Partir de la Classification Internationale des Maladies [From Classification to Knowledge About Diseases: Thoughts about the International Classification of Diseases] Innovation et Technologie en Biologie et Médecine. 2000;21(5):291-97.
Bodenreider O, Mitchell JA, McCray AT. Evaluation of the UMLS as a Terminology and Knowledge Resource for Biomedical Informatics Proc AMIA Symp. 2002:61-65.
Jacquelinet C, Bodenreider O, Burgun A. Modelling Syllepse in Medical Knowledge Bases with Application in the Domain of Organ Failure and Transplantation Proc. of OntoLex; Workshop on Ontologies and Lexical Knowledge Bases 2000.
Bodenreider O, Rindflesch TC, Burgun A. Unsupervised, Corpus-Based Method for Extending a Biomedical Terminology Proc. of the ACL Workshop; Natural Language Processing in the Biomedical Domain. 2002;:53-60.
McCray AT, Bodenreider O. A Conceptual Framework for the Biomedical Domain The Semantics of Relationships: An Interdisciplinary Perspective. Boston: Kluwer Academic Publishers. 2002;:181-198.
Mitchell JA, McCray AT, Bodenreider O. From Phenotype to Genotype: Navigating the Available Information Resources Proc AMIA Symp. 2002;:1109.
Srinivasan P, Mitchell JA, Bodenreider O, Pant G, Menczer F. Web Crawling Agents for Retrieving Biomedical Information Proc. of the International Workshop on Bioinformatics and Multi-Agent Systems (BIXMAS). 2002 Jul.
Bodenreider O, Burgun A, Rindflesch TC. Lexically-Suggested Hyponymic Relations Among Medical Terms and Their Representation in the UMLS Proc. of TIA'2001; Terminology and Artificial Intelligence. 2001;:11-21.
McCray AT. An Upper Level Ontology for the Biomedical Domain Comp Funct Genom. 2003;4:80-4.
Bodenreider O, Burgun A, Mitchell JA. Evaluation of WordNet as a Source of Lay Knowledge for Molecular Biology and Genetic Diseases: A Feasibility Study Stud Health Technol Inform. 2003;95:379-84.

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