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Medical Ontology Research

The LHNCBC Medical Ontology Research project encompasses basic research on biomedical terminologies and ontologies and their applications to natural language processing, clinical decision support, translational medicine, data integration and interoperability. In the past few years, our research has focused on the integration, dissemination, quality assurance and applications of drug ontologies (add link to the 2014 BoSC report) and on quality assurance in biomedical ontologies. We also develop application programming interfaces (APIs) and browsers for drug resources including RxNorm, RxTerms, NDF-RT and ATC.

Peters LB, Bahr N, Bodenreider O. Evaluating drug-drug interaction information in NDF-RT and DrugBank. J Biomed Semantics. 2015 May 11;6:19. doi: 10.1186/s13326-015-0018-0. eCollection 2015.
Winnenburg R, Sorbello A, Bodenreider O. Exploring adverse drug events at the class level. J Biomed Semantics. 2015 May 1;6:18. doi: 10.1186/s13326-015-0017-1. eCollection 2015.
Winnenburg R, Mortensen JM, Bodenreider O. Using description logics to evaluate the consistency of drug-class membership relations in NDF-RT. J Biomed Semantics. 2015 Mar 28;6:13. doi: 10.1186/s13326-015-0007-3. eCollection 2015.
Rance B, Le T, Bodenreider O. Fingerprinting Biomedical Terminologies--Automatic Classification and Visualization of Biomedical Vocabularies through UMLS Semantic Group Profiles. Stud Health Technol Inform. 2015;216:771-5.
Fung KW, Richesson R, Bodenreider O. Coverage of rare disease names in standard terminologies and implications for patients, providers, and research. AMIA Annu Symp Proc. 2014 Nov 14;2014:564-72. eCollection 2014.
Winnenburg R, Bodenreider O. Desiderata for an authoritative Representation of MeSH in RDF. AMIA Annu Symp Proc. 2014 Nov 14;2014:1218-27. eCollection 2014.
Harpaz R, Odgers D, Gaskin G, DuMouchel W, Winnenburg R, Bodenreider O, Ripple AM, Szarfman A, Sorbello A, Horvitz E, White RW, Shah NH. A time-indexed reference standard of adverse drug reactions. Sci Data. 2014 Nov 11;1:140043. doi: 10.1038/sdata.2014.43.
Winnenburg R, Bodenreider O. Desiderata for an authoritative representation of MeSH in RDF. AMIA Annu Symp Proc 2014:1218-1227.
Khatipov E, Madden M, Chiang P, Chuang P, Nguyen D, D'Souza I, Winnenburg R, Bodenreider O, Skapik J, McClure R, Emrick S. Creating, maintaining and publishing value sets in the VSAC. AMIA Annu Symp Proc, 2014: p. 1459.
Nguyen T, Peters L, Bodenreider O. RxClass - Navigating between drug classes and RxNorm drugs. AMIA Annu Symp Proc, 2014: p. 1529.