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Biomedical Data Visualization

Illustration of intra-cellular organelles (mitochondria and endoplasmic reticulum) of a melanoma cancer cell.
Project information
Researchers: 

LHNCBC's Biomedical Data Visualization contributes to improving access to high quality biomedical imaging information. This project includes:

  • The APDB/NCI collaboration on 3D visualization of molecular structures and functions in the discovery of disease and treatment
  • The Movement Disorders Database (a digital archive of movement disorders patients going through diagnostic routines, and development of interactive tools and applications which utilize video for clinical monitoring and diagnostics)
  • The Profiles in Science video modules
  • The Visible Human imaging and visualization research
Publications/Tools: 
Guo P, Stanley RJ, De S, Long LR, Antani SK, Thoma GR, Demner-Fushman D, Sornapudia S. Features Advances to Automatically Find Images for Application to Clinical Decision Support. Medical Research Archives. 4(7) 2016. DOI: 10.18103/mra.v4i7.761
Pedrosa G, Rahman MM, Antani SK, Demner-Fushman D, Long LR, Traina A. Integrating visual words as bunch of n-grams for effective biomedical image classification. Proceedings of IEEE WACV 2014: IEEE Winter Conference on Applications of Computer Vision. Steamboat Springs, CO. March 24-26, 2014.
Rahman MM, Antani SK, Demner-Fushman D, Thoma GR. An Interactive Region-Of-interest (ROI)- Based Image Retrieval Approach of Biomedical Articles in a Local Concept- Based Feature Space. NIH Intramural Research Festival, Bethesda MD, November 6-8, 2013.
Meyerson JR, White TA, Bliss D, Moran A, Bartesaghi A, Borgnia MJ, de la Cruz JV, Schauder D, Hartnell LM, Nandwani R, Dawood M, Kim B, Kim JH, Sununu J, Yang L, Bhatia S, Subramaniam C, Hurt DE, Gaudreault L, Subramaniam S. Determination of molecular structures of HIV envelope glycoproteins using cryo-electron tomography and automated sub-tomogram averaging. J Vis Exp. 2011 Dec 1;(58). pii: 2770. doi: 10.3791/2770.
Butan C, Hartnell LM, Fenton AK, Bliss D, Sockett RE, Subramaniam S, Milne JL. Spiral architecture of the nucleoid in Bdellovibrio bacteriovorus. J Bacteriol. 2011 Mar;193(6):1341-50. doi: 10.1128/JB.01061-10. Epub 2010 Dec 10.
Felts RL, Narayan K, Estes JD, Shi D, Trubey CM, Fu J, Hartnell LM, Ruthel GT, Schneider DK, Nagashima K, Bess JW Jr, Bavari S, Lowekamp B, Bliss D, Lifson JD, Subramaniam S. 3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13336-41. doi: 10.1073/pnas.1003040107. Epub 2010 Jul 12.
Guan H, Antani S, Long LR, Thoma GR. Minimizing the Semantic Gap In Biomedical Content-based Image Retrieval Proc SPIE, Medical Imaging: Advanced PACS-based Imaging Informatics, and Therapeutic Applications. March 2010;7628:762807-1 ~ 762807-8
Kim E, Huang X, Tan G, Long LR, Antani S. A Hierarchical SVG Image Abstraction Layer for Medical Imaging Medical Imaging 2010: Advanced PACS-based Imaging Informatics and Therapeutic Applications. San Diego, California. March 2010;7628
Heymann JAW, Shi D, Kim S, Bliss D, Milne JLS, Subramaniam S. 3D imaging of mammalian cells with ion-abrasion scanning electron microscopy. J Struct Biol. 2009 Apr;166(1):1-7. doi: 10.1016/j.jsb.2008.11.005. Epub 2008 Dec 10.
Zhan Zhang, Ackerman MJ, Jixing Li. A Prototype Colon Straightening System for Polyp Detection. Proceedings of 17th IEEE Symposium on Computer-Based Medical Systems (CBMS); 2004 Jun 24-25; Bethesda, Maryland:548-52. DOI: 10.1109/CBMS.2004.1311772.