Drug Interaction API
The Interaction API is a web service for accessing drug-drug interactions.
Currently, the API uses two sources for its interaction information - ONCHigh and DrugBank.
ONCHigh is a list of high-priority drug-drug interactions derived by a panel of experts and contained in a JAMIA article. ONCHigh is updated using CredibleMeds with drugs that have a known risk of Torsades de Pointes (TdP).
DrugBank drug-drug interaction information is drawn from the DrugBank database. The data shared with us by DrugBank do not carry severity information.
The drug-drug interactions are updated monthly, usually on the first Monday of the month.
Use of the API is subject to Terms of Service. No license is needed to use the Interaction API.
API calls that cannot be processed, because of invalid parameters, will result in HTTP error code 400 ("Bad Request").
For details, see API Changes - On or After July 5, 2021.
REST resources (API function results) will no longer echo your query parameters.
For details, see API Changes - On or After August 2, 2021.